Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name crq
Flybase description The gene croquemort is referred to in FlyBase by the symbol Dmel\crq (CG4280, FBgn0015924).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.4855 1.6502 -2.713652 1.5228 -0.627928 -0.452 -0.55399 -0.730975
    Affimetrix absolute value 8.97 8.304 6.764 8.976 8.424 8.406 8.294 7.844
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: scavenger receptor activity.
There is experimental evidence that it is involved in the biological process: phagocytosis triggered by activation of immune response cell surface activating receptor; apoptosis; phagocytosis; autophagic cell death; salivary gland cell autophagic cell death.
14 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval glial cell; presumptive embryonic/larval central nervous system.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: CD36 antigen.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.