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|Flybase description||The gene disc proliferation abnormal is referred to in FlyBase by the symbol Dmel\dpa (CG1616, FBgn0015929).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 3'-5' DNA helicase activity.
There is experimental evidence that it is involved in the biological process: mitotic spindle organization; DNA replication.
13 alleles are reported.
The phenotypes of these alleles are annotated with: chromosome, centromeric region; trichogen cell; central nervous system; mitotic cell cycle; spindle; mesothoracic tergum; imaginal disc; mitotic metaphase.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ATPase, AAA+ type, core; Mini-chromosome maintenance complex protein 4; Mini-chromosome maintenance, DNA-dependent ATPase; Mini-chromosome maintenance, conserved site; Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like; Rubredoxin-type Fe(Cys)4 protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.