Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name grim
Flybase description The gene grim is referred to in FlyBase by the symbol Dmel\grim (CG4345, FBgn0015946).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -79.3328 -44.8192 -65.608321 -69.8786 -94.380308 -78.9072 -79.0603 -66.537908
    Affimetrix absolute value 2.105 2.137 2.15 2.268 2.2 2.262 2.253 2.219
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: apoptosis; melanization defense response; induction of apoptosis; determination of adult lifespan; negative regulation of neuron apoptosis; positive regulation of programmed cell death.
55 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; multicellular structure; external compound sense organ; embryonic/larval neuron; adult segment; non-connected developing system; embryonic/larval corpus allatum; pioneer neuron; peripheral nervous system.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-18 hour embryonic stages.