Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sema-1b
Flybase description The gene Sema-1b is referred to in FlyBase by the symbol Dmel\Sema-1b (CG6446, FBgn0016059).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.8081 -3.8072 -9.032081 -4.4418 -14.058625 -5.1785 -2.2838 -9.279148
    Affimetrix absolute value 6.923 5.732 5.024 6.268 4.974 6.198 7.391 5.156
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: receptor activity.
There is experimental evidence that it is involved in the biological process: embryonic development via the syncytial blastoderm.
10 alleles are reported.
The phenotype of these alleles is annotated with: intersegmental nerve.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Plexin-like fold; Plexin/semaphorin/integrin; Semaphorin/CD100 antigen; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.