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|Flybase description||The gene Cyclin-dependent kinase 4 is referred to in FlyBase by the symbol Dmel\Cdk4 (CG5072, FBgn0016131).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cyclin binding.
There is experimental evidence that it is involved in the biological process: blastoderm segmentation; cell proliferation; cell growth; JAK-STAT cascade; cell cycle; mitochondrion organization; open tracheal system development.
35 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; adult; abdominal 4 ventral denticle belt; cell cycle; mesothoracic tergum; wing; embryo; denticle belt.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 06-12 hour embryonic stages.