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|Flybase description||The gene frizzled 2 is referred to in FlyBase by the symbol Dmel\fz2 (CG9739, FBgn0016797).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Wnt receptor activity; PDZ domain binding; Wnt-protein binding.
There is experimental evidence that it is involved in the biological process: female gonad development; cellular component movement; imaginal disc-derived wing margin morphogenesis; receptor-mediated endocytosis; retinal ganglion cell axon guidance; bristle morphogenesis; Wnt receptor signaling pathway; axon extension; salivary gland morphogenesis; synapse organization.
117 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; adult segment; external compound sense organ; peripheral nervous system; synapse; acellular anatomical structure; thoracic segment; embryonic/larval neuron; postsynaptic membrane; embryonic foregut.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Frizzled domain; Frizzled protein; Frizzled-related; GPCR, family 2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.