Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name spen
Flybase description The gene split ends is referred to in FlyBase by the symbol Dmel\spen (CG18497, FBgn0016977).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.1339 2.1596 -0.472529 1.4651 -2.521757 0.4929 1.55874 -2.04523
    Affimetrix absolute value 8.239 8.714 8.016 8.917 7.543 8.762 9.14 7.385
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding; nucleic acid binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; system development; cellular component organization or biogenesis; post-embryonic organ morphogenesis; cell fate commitment; cellular process; appendage development; neuroblast fate commitment; localization; sensory organ development; segment specification.
96 alleles are reported.
The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; peripheral nervous system; external compound sense organ; pharyngeal sclerite; acellular anatomical structure; eo support cell; non-connected developing system; embryonic thorax.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; Spen Paralogue and Orthologue SPOC, C-terminal-like; Spen paralogue and orthologue SPOC, C-terminal; Spen paralogue/orthologue C-terminal, metazoa.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.