|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene split ends is referred to in FlyBase by the symbol Dmel\spen (CG18497, FBgn0016977).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding; nucleic acid binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; system development; cellular component organization or biogenesis; post-embryonic organ morphogenesis; cell fate commitment; cellular process; appendage development; neuroblast fate commitment; localization; sensory organ development; segment specification.
96 alleles are reported.
The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; peripheral nervous system; external compound sense organ; pharyngeal sclerite; acellular anatomical structure; eo support cell; non-connected developing system; embryonic thorax.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; Spen Paralogue and Orthologue SPOC, C-terminal-like; Spen paralogue and orthologue SPOC, C-terminal; Spen paralogue/orthologue C-terminal, metazoa.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.