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|Flybase description||The gene skittles is referred to in FlyBase by the symbol Dmel\sktl (CG9985, FBgn0016984).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 1-phosphatidylinositol-4-phosphate 5-kinase activity.
There is experimental evidence that it is involved in the biological process: spermatid development; maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification; oocyte microtubule cytoskeleton polarization; autophagic cell death; cortical actin cytoskeleton organization; salivary gland cell autophagic cell death; peripheral nervous system development.
35 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: multicellular structure; anatomical structure; cytoplasmic part; cell part; organ system; organ system subdivision; adult segment; acellular anatomical structure; egg; thoracic segment; sense organ; non-connected developing system; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Phosphatidylinositol-4-phosphate 5-kinase; Phosphatidylinositol-4-phosphate 5-kinase, core; Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.