Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Rca1
Flybase description The gene Regulator of cyclin A1 is referred to in FlyBase by the symbol Dmel\Rca1 (CG10800, FBgn0017551).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.5404 -3.6602 -5.193949 -5.7028 -6.898675 -6.9159 -7.52187 -7.073164
    Affimetrix absolute value 6.227 5.759 5.827 5.889 5.974 5.792 5.671 5.489
    Affymetric present call in "x" number of chips 3 3 2 3 0 2 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: negative regulation of mitotic anaphase-promoting complex activity; lateral inhibition; G1/S transition of mitotic cell cycle; neurogenesis.
22 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: anatomical structure; embryonic/larval neuron; organ system; multicellular structure; organ system subdivision; embryonic pericardial cell; external compound sense organ; portion of tissue; sense organ; ganglion mother cell GMC4-2a; cardioblast; ganglion mother cell GMC1-1a; imaginal precursor; peripheral nervous system.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.