Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name gcm2
Flybase description The gene gcm2 is referred to in FlyBase by the symbol Dmel\gcm2 (CG3858, FBgn0019809).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -43.0738 -24.6288 -40.14054 -39.6793 -55.406921 -45.2329 -49.94531 -41.468236
    Affimetrix absolute value 2.987 3.031 2.885 3.078 2.976 3.064 2.909 2.955
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: embryonic crystal cell differentiation; glial cell differentiation; cell proliferation; dendrite morphogenesis; glial cell development; negative regulation of crystal cell differentiation; gliogenesis; neuron differentiation; plasmatocyte differentiation.
9 alleles are reported.
The phenotypes of these alleles are annotated with: crystal cell primordium; crystal cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Transcription regulator, GCM-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed within 06-12 hour embryonic stages.