Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Cdk9
Flybase description The gene Cyclin-dependent kinase 9 is referred to in FlyBase by the symbol Dmel\Cdk9 (CG5179, FBgn0019949).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.5456 -2.5987 -4.581268 -2.8665 -5.864989 -3.3148 -3.78206 -5.921458
    Affimetrix absolute value 7.076 6.245 6.036 6.869 6.238 6.835 6.661 5.766
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cyclin-dependent protein kinase activity; RNA polymerase II carboxy-terminal domain kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; transcription elongation from RNA polymerase II promoter; transcription, DNA-dependent; cell adhesion; response to heat; cell cycle; neurogenesis.
14 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.