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|Flybase description||The gene sulfateless is referred to in FlyBase by the symbol Dmel\sfl (CG8339, FBgn0020251).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: [heparan sulfate]-glucosamine N-sulfotransferase activity.
There is experimental evidence that it is involved in the biological process: fibroblast growth factor receptor signaling pathway; glycosaminoglycan biosynthetic process; mesoderm migration involved in gastrulation; synaptic vesicle endocytosis; intracellular distribution of mitochondria; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; sulfur compound metabolic process; Wnt receptor signaling pathway; segment polarity determination; epithelial cell migration, open tracheal system.
17 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; multicellular structure; portion of tissue; tracheal system; anatomical structure; acellular anatomical structure; organ system subdivision; non-connected developing system; synapse; embryonic/larval integumentary system; adult segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Heparan sulphate-N-deacetylase; Sulfotransferase domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages.