Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pcm
Flybase description The gene pacman is referred to in FlyBase by the symbol Dmel\pcm (CG3291, FBgn0020261).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.1945 -3.9643 -4.423811 -7.968 -8.178943 -7.8802 -13.25758 -8.450313
    Affimetrix absolute value 4.702 5.637 6.055 5.431 5.742 5.602 4.855 5.236
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 5'-3' exoribonuclease activity.
There is experimental evidence that it is involved in the biological process: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; dorsal closure; RNA interference; regulation of cytoplasmic mRNA processing body assembly; wound healing; imaginal disc fusion, thorax closure; nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'; imaginal disc-derived wing morphogenesis; spermatogenesis.
12 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; testis; mesothoracic tergum; wing; spermatozoon.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: 5'-3' exoribonuclease 1; Putative 5-3 exonuclease.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.