Flygut: an atlas of the Drosophila adult midgut

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Gene name mre11
Flybase description The gene meiotic recombination 11 is referred to in FlyBase by the symbol Dmel\mre11 (CG16928, FBgn0020270).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.4073 -4.883 -7.88207 -5.5117 -8.15716 -5.5974 -9.04123 -8.693265
    Affimetrix absolute value 5.735 5.356 5.236 5.985 5.748 6.098 5.374 5.144
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: endonuclease activity; exonuclease activity.
There is experimental evidence that it is involved in the biological process: G2/M transition DNA damage checkpoint; response to DNA damage stimulus; telomere maintenance; chromosome organization; telomere capping.
12 alleles are reported.
The phenotype of these alleles is annotated with: chromosome, telomeric region.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: DNA repair exonuclease; Metallophosphoesterase domain; Mre11, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.