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|Flybase description||The gene domino is referred to in FlyBase by the symbol Dmel\dom (CG9696, FBgn0020306).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: gene silencing; chromatin organization; negative regulation of gene expression; instar larval or pupal development; positive regulation of Notch signaling pathway; oogenesis; wing disc pattern formation; regulation of alternative nuclear mRNA splicing, via spliceosome; neurogenesis; dendrite guidance.
31 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; multicellular structure; imaginal precursor; organ system subdivision; anatomical structure; embryonic/larval hemocoel; adult segment; embryonic/larval imaginal precursor; eo support cell; circulatory system; late extended germ band embryo.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: DEAD-like helicase; HAS subgroup; HSA; Helicase, C-terminal; Helicase/SANT-associated, DNA binding; MYB-like; SNF2-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.