|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene Death related ced-3/Nedd2-like protein is referred to in FlyBase by the symbol Dmel\Dredd (CG7486, FBgn0020381).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; apoptotic protease activator activity; endopeptidase activity.
There is experimental evidence that it is involved in the biological process: immune response; apoptosis; peripheral nervous system neuron development; sperm individualization; defense response to Gram-negative bacterium; peptidoglycan recognition protein signaling pathway; defense response; protein maturation by peptide bond cleavage.
31 alleles are reported.
The phenotypes of these alleles are annotated with: spermatid; mesothoracic tergum.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed during late larval stages, at stages throughout the pupal period.