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|Flybase description||The gene Pcaf is referred to in FlyBase by the symbol Dmel\Pcaf (CG4107, FBgn0020388).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: H3 histone acetyltransferase activity; H4 histone acetyltransferase activity.
There is experimental evidence that it is involved in the biological process: histone H3 acetylation; dendrite morphogenesis; histone H4 acetylation; muscle organ development; regulation of histone acetylation; axon target recognition.
20 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; organ system; adult segment; external compound sense organ; thoracic segment; adult; appendage segment; peripheral nervous system; eo support cell; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Acyl-CoA N-acyltransferase; Bromodomain; Bromodomain, conserved site; GCN5-related N-acetyltransferase (GNAT) domain; Histone acetylase PCAF; PCAF, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.