Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Nmt
Flybase description The gene N-myristoyl transferase is referred to in FlyBase by the symbol Dmel\Nmt (CG7436, FBgn0020392).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.2856 1.1513 0.344479 0.4974 -1.582574 0.3467 -1.61017 -1.400858
    Affimetrix absolute value 7.247 7.82 8.19 8.592 8.126 8.582 7.89 7.818
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glycylpeptide N-tetradecanoyltransferase activity.
There is experimental evidence that it is involved in the biological process: N-terminal protein myristoylation; neurogenesis.
2 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; multicellular structure; anatomical structure; non-connected developing system; organ system subdivision; portion of tissue; acellular anatomical structure; extended germ band embryo; spiracle; cephalopharyngeal skeleton.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Acyl-CoA N-acyltransferase; Myristoyl-CoA:protein N-myristoyltransferase; Myristoyl-CoA:protein N-myristoyltransferase, C-terminal; Myristoyl-CoA:protein N-myristoyltransferase, N-terminal; Myristoyl-CoA:protein N-myristoyltransferase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.