Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name GluRIIB
Flybase description The gene Glutamate receptor IIB is referred to in FlyBase by the symbol Dmel\GluRIIB (CG7234, FBgn0020429).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -33.6054 -21.3913 -30.56304 -41.2324 -43.401965 -40.4081 -37.13259 -30.809464
    Affimetrix absolute value 3.357 3.212 3.266 3.028 3.33 3.231 3.348 3.371
    Affymetric present call in "x" number of chips 1 0 0 1 0 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glutamate receptor activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport.
12 alleles are reported.
The phenotype of these alleles is annotated with: neuromuscular junction.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Extracellular ligand-binding receptor; Extracellular solute-binding protein, family 3; Glutamate receptor, L-glutamate/glycine-binding; Ionotropic glutamate receptor; NMDA receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed within 12-18 embryonic stages.