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|Flybase description||The gene C-terminal Binding Protein is referred to in FlyBase by the symbol Dmel\CtBP (CG7583, FBgn0020496).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; transcription factor binding; protein homodimerization activity; transcription corepressor activity; transcription coactivator activity.
There is experimental evidence that it is involved in the biological process: bristle development; wing disc development; regulation of Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; embryonic development via the syncytial blastoderm; regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway.
64 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: adult segment; organ system subdivision; organ system; thoracic segment; adult; integumentary plate; sense organ; multicellular structure; embryonic/larval hemocoel; eo support cell.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; NAD(P)-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-12 hour embryonic stages.