Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ade5
Flybase description The gene ade5 is referred to in FlyBase by the symbol Dmel\ade5 (CG3989, FBgn0020513).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.8828 -1.5633 -3.918683 -4.2203 -5.683842 -4.3166 0.5307 -2.703601
    Affimetrix absolute value 6.92 6.975 6.216 6.318 6.258 6.473 8.734 6.846
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; phosphoribosylaminoimidazole carboxylase activity.
There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior.
14 alleles are reported.
The phenotype of these alleles is annotated with: pigment cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ATP-grasp fold, subdomain 2; Phosphoribosylaminoimidazole carboxylase, core; SAICAR synthetase; SAICAR synthetase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed during late larval stages, during early pupal stages, in stages of adults of both sexes.