Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name eIF-4B
Flybase description The gene Eukaryotic initiation factor 4B is referred to in FlyBase by the symbol Dmel\eIF-4B (CG10837, FBgn0020660).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -16.4676 -9.0735 -9.845973 -15.1256 -18.845868 -17.7161 -16.65027 -13.151555
    Affimetrix absolute value 4.374 4.45 4.897 4.477 4.535 4.415 4.496 4.551
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: translation initiation factor activity.
There is experimental evidence that it is involved in the biological process: cell proliferation; translational initiation.
9 alleles are reported.
The phenotypes of these alleles are annotated with: eye; ommatidium.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.
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