Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name chb
Flybase description The gene chromosome bows is referred to in FlyBase by the symbol Dmel\chb (CG32435, FBgn0021760).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5153 2.1456 -0.227924 -0.3755 -2.116305 -1.2404 1.52024 -0.091187
    Affimetrix absolute value 7.809 8.714 8.28 8.335 7.728 8.253 9.113 7.875
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: GTP binding; microtubule binding.
There is experimental evidence for 17 unique biological process terms, many of which group under: cellular component organization or biogenesis; cell cycle; cell cycle process; biological regulation; multicellular organism reproduction; organelle organization; localization; gamete generation; regulation of cellular component organization; cellular component movement; fusome organization; regulation of developmental process; establishment or maintenance of cytoskeleton polarity; neuron differentiation.
37 alleles are reported.
The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system; multicellular structure; organelle; cytoplasmic part; organ system subdivision; intracellular organelle part; embryonic/larval neuron; external compound sense organ; centrosome; cell cycle.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Armadillo-like helical; Armadillo-type fold; HEAT, type 2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout the pupal period, in adult male stages.