Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sdk
Flybase description The gene sidekick is referred to in FlyBase by the symbol Dmel\sdk (CG5227, FBgn0021764).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -20.1869 -8.8741 -22.078649 -7.8916 -31.040195 -18.306 -22.96842 -26.445142
    Affimetrix absolute value 4.08 4.489 3.732 5.423 3.846 4.37 4.077 3.56
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: negative regulation of photoreceptor cell differentiation; compound eye cone cell differentiation; pigment cell differentiation.
33 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor; eye; interommatidial bristle; cone cell; lens; ommatidium; mystery cell; pigment cell.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.