Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mira
Flybase description The gene miranda is referred to in FlyBase by the symbol Dmel\mira (CG12249, FBgn0021776).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -28.005 -6.5267 -4.807677 -6.1803 -5.354711 -6.6383 -22.04125 -6.044803
    Affimetrix absolute value 3.607 4.938 5.955 5.77 6.345 5.841 4.099 5.654
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; myosin binding.
There is experimental evidence that it is involved in the biological process: neuroblast proliferation; regulation of pole plasm oskar mRNA localization; asymmetric protein localization; oogenesis; regulation of proteolysis; anterior/posterior axis specification, embryo.
30 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: multicellular structure; organ system; anatomical structure; organ system subdivision; portion of tissue; ventral nerve cord primordium; embryonic/larval cell body glial cell; embryonic/larval neuron; extended germ band embryo; embryonic thorax.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Prefoldin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.