Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Tor
Flybase description The gene Target of rapamycin is referred to in FlyBase by the symbol Dmel\Tor (CG5092, FBgn0021796).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.4089 -1.93 -3.618208 -2.7302 -5.960721 -3.4512 -0.51115 -5.321119
    Affimetrix absolute value 6.268 6.671 6.373 6.964 6.218 6.783 8.354 5.952
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein self-association.
There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; cellular process; system development; multicellular organismal development; response to DNA damage stimulus; positive regulation of ribosome biogenesis; endocytic recycling; determination of adult lifespan; growth; catabolic process.
36 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; organelle; multicellular structure; organ system subdivision; cytoplasmic part; intracellular organelle; portion of tissue; salivary gland imaginal ring; embryonic/larval fat body; nucleus; cell cycle; external compound sense organ; adult segment; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-like helical; Armadillo-type fold; FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding; PIK-related kinase; PIK-related kinase, FAT; PIK-related kinase, FATC; Phosphatidylinositol 3-/4-kinase, catalytic; Phosphatidylinositol 3/4-kinase, conserved site; Protein kinase-like domain; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.