Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Xbp1
Flybase description The gene X box binding protein-1 is referred to in FlyBase by the symbol Dmel\Xbp1 (CG9415, FBgn0021872).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.9928 6.4514 4.671964 2.7637 1.980046 1.9005 2.8269 3.519009
    Affimetrix absolute value 9.984 10.306 10.395 9.83 9.738 9.472 10.032 10.052
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: bristle development; endoplasmic reticulum unfolded protein response; wing disc development; lateral inhibition; response to endoplasmic reticulum stress.
12 alleles are reported.
The phenotypes of these alleles are annotated with: eye; eye photoreceptor cell; tormogen cell; scutellar bristle; wing; imaginal disc; scutum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Basic leucine zipper; Basic-leucine zipper (bZIP) transcription factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.