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|Flybase description||The gene Vacuolar protein sorting 25 is referred to in FlyBase by the symbol Dmel\Vps25 (CG14750, FBgn0022027).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: regulation of apoptosis; regulation of multivesicular body size involved in endosome transport; cell proliferation; negative regulation of epithelial cell proliferation; regulation of Notch signaling pathway; endosome transport via multivesicular body sorting pathway; epithelial structure maintenance; maintenance of epithelial cell apical/basal polarity; cell differentiation; endosome transport.
17 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval digestive system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ESCRT-II complex, vps25 subunit; ESCRT-II complex, vps25 subunit, C-terminal winged helix; ESCRT-II complex, vps25 subunit, N-terminal winged helix.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 00-12 hour embryonic stages.