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|Flybase description||The gene CAS/CSE1 segregation protein is referred to in FlyBase by the symbol Dmel\Cas (CG13281, FBgn0022213).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: importin-alpha export receptor activity.
There is experimental evidence that it is involved in the biological process: protein export from nucleus; positive regulation of NFAT protein import into nucleus; neurogenesis; phagocytosis, engulfment.
21 alleles are reported.
The phenotypes of these alleles are annotated with: egg; macrochaeta; thecogen cell; microchaeta; tergite; eo neuron.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-like helical; Armadillo-type fold; CAS/CSE, C-terminal; Exportin/Importin, Cse1-like; Importin-beta, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.