Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pp2C1
Flybase description The gene Protein phosphatase 2C is referred to in FlyBase by the symbol Dmel\Pp2C1 (CG2984, FBgn0022768).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.0915 -3.5046 -4.416173 -6.0211 -7.849538 -6.9415 -6.92129 -5.872195
    Affimetrix absolute value 5.614 5.816 6.059 5.805 5.794 5.772 5.767 5.731
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine phosphatase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: protein dephosphorylation.
6 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Fumarate reductase/succinate dehydrogenase, FAD-binding site; Protein phosphatase 2C; Protein phosphatase 2C, manganese/magnesium aspartate binding site; Protein phosphatase 2C-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.