Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hira
Flybase description The gene Hira is referred to in FlyBase by the symbol Dmel\Hira (CG12153, FBgn0022786).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.132 -4.1439 -3.915898 -6.8845 -6.156116 -5.3561 -12.54796 -6.103079
    Affimetrix absolute value 5.077 5.569 6.213 5.606 6.136 6.162 4.932 5.657
    Affymetric present call in "x" number of chips 0 2 3 3 3 3 1 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: chromatin binding.
There is experimental evidence that it is involved in the biological process: fertilization, exchange of chromosomal proteins; sperm chromatin decondensation; DNA replication-independent nucleosome assembly; chromatin remodeling.
10 alleles are reported.
The phenotype of these alleles is annotated with: male pronucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: G-protein beta WD-40 repeat; HIRA B motif; Quinonprotein alcohol dehydrogenase-like; TUP1-like enhancer of split; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.