Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Cbp80
Flybase description The gene cap binding protein 80 is referred to in FlyBase by the symbol Dmel\Cbp80 (CG7035, FBgn0022942).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -56.6807 -34.5096 -48.211869 -55.3958 -77.443787 -52.6639 -59.51482 -65.331
    Affimetrix absolute value 2.604 2.523 2.594 2.606 2.484 2.846 2.678 2.279
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: RNA cap binding.
There is experimental evidence that it is involved in the biological process: production of siRNA involved in RNA interference; negative regulation of viral genome replication; gene silencing by miRNA; neurogenesis.
4 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo-type fold; MIF4-like, type 1/2/3; MIF4G-like, type 1; MIF4G-like, type 2; MIF4G-like, type 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.