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|Flybase description||The gene Clock is referred to in FlyBase by the symbol Dmel\Clk (CG7391, FBgn0023076).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein heterodimerization activity; DNA binding.
There is experimental evidence that it is involved in the biological process: regulation of circadian sleep/wake cycle, sleep; circadian rhythm; locomotor rhythm; positive regulation of transcription, DNA-dependent; circadian regulation of gene expression.
27 alleles are reported.
The phenotype of these alleles is annotated with: larval LN period neuron.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Nuclear translocator; PAC motif; PAS; PAS fold-3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed in adult male stages.