Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cyc
Flybase description The gene cycle is referred to in FlyBase by the symbol Dmel\cyc (CG8727, FBgn0023094).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.0361 -2.4112 -3.466675 -2.7065 -4.758096 -3.4225 -4.54228 -3.987417
    Affimetrix absolute value 6.81 6.356 6.419 6.96 6.557 6.798 6.386 6.291
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein heterodimerization activity; DNA binding.
There is experimental evidence that it is involved in the biological process: response to starvation; regulation of circadian sleep/wake cycle, sleep; circadian regulation of gene expression.
16 alleles are reported.
The phenotype of these alleles is annotated with: LN period neuron.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Nuclear translocator; PAC motif; PAS; PAS fold; PAS fold-3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.