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|Flybase description||The gene SNF1A/AMP-activated protein kinase is referred to in FlyBase by the symbol Dmel\SNF1A (CG3051, FBgn0023169).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: AMP-activated protein kinase activity.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle; regulation of cell growth; protein phosphorylation; establishment or maintenance of epithelial cell apical/basal polarity; regulation of digestive system process; phagocytosis, engulfment.
28 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval midgut; circular visceral muscle fiber; midgut muscle; hindgut muscle; embryonic/larval digestive system; embryonic/larval fat body; hindgut visceral muscle fiber; sensory neuron; longitudinal visceral muscle fiber.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, in stages of adults of both sexes.