Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name SNF1A
Flybase description The gene SNF1A/AMP-activated protein kinase is referred to in FlyBase by the symbol Dmel\SNF1A (CG3051, FBgn0023169).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.8834 2.9264 2.456329 1.8909 1.214034 1.2393 1.85476 1.798173
    Affimetrix absolute value 9.318 9.165 9.46 9.297 9.032 8.857 9.429 9.053
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: AMP-activated protein kinase activity.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle; regulation of cell growth; protein phosphorylation; establishment or maintenance of epithelial cell apical/basal polarity; regulation of digestive system process; phagocytosis, engulfment.
28 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval midgut; circular visceral muscle fiber; midgut muscle; hindgut muscle; embryonic/larval digestive system; embryonic/larval fat body; hindgut visceral muscle fiber; sensory neuron; longitudinal visceral muscle fiber.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, in stages of adults of both sexes.