Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG3573
Flybase description The gene Oculocerebrorenal syndrome of Lowe 1 ortholog is referred to in FlyBase by the symbol Dmel\Ocrl (CG3573, FBgn0023508).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.1935 0.2958 -1.764324 -1.7321 -3.024011 -2.4402 -1.93781 -2.198417
    Affimetrix absolute value 6.735 7.573 7.371 7.615 7.179 7.3 7.621 7.135
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: inositol or phosphatidylinositol phosphatase activity.
There is experimental evidence that it is involved in the biological process: phosphatidylinositol dephosphorylation; endocytosis; regulation of cytokinesis, actomyosin contractile ring assembly; contractile ring localization involved in cell cycle cytokinesis; cell cycle cytokinesis.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Endonuclease/exonuclease/phosphatase; Inositol polyphosphate-related phosphatase; PapD-like; Rho GTPase activation protein; Rho GTPase-activating protein domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.