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|Flybase description||The gene wishful thinking is referred to in FlyBase by the symbol Dmel\wit (CG10776, FBgn0024179).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: transforming growth factor beta receptor activity, type II.
There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; lateral inhibition; neuromuscular junction development.
36 alleles are reported.
The phenotypes of these alleles are annotated with: wing vein L5; posterior crossvein; NMJ bouton; bouton; chaeta; neuromuscular junction; embryonic/larval neuromuscular junction; postsynaptic membrane; synapse; embryonic/larval muscle system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase-like domain; TGF-beta receptor/activin receptor, type I/II.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed during early pupal stages.