Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name ial
Flybase description The gene IplI-aurora-like kinase is referred to in FlyBase by the symbol Dmel\ial (CG6620, FBgn0024227).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -39.7126 -19.101 -24.438292 -21.8996 -25.299704 -24.1196 -36.94275 -28.695406
    Affimetrix absolute value 3.114 3.37 3.584 3.946 4.107 4.048 3.348 3.44
    Affymetric present call in "x" number of chips 0 0 0 1 1 1 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: mitotic chromosome condensation; chromatin organization; mitotic spindle organization; cytokinesis; histone phosphorylation; mitotic sister chromatid segregation; neurogenesis.
8 alleles are reported.
The phenotypes of these alleles are annotated with: mitotic cell cycle; mitotic anaphase; spindle; mesothoracic tergum; nucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.