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|Flybase description||The gene chico is referred to in FlyBase by the symbol Dmel\chico (CG5686, FBgn0024248).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: insulin-like growth factor receptor binding.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; multicellular organism reproduction; cellular component organization or biogenesis; growth; response to stress; developmental growth; gamete generation; male germ-line stem cell division; response to nutrient levels; aging.
17 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; adult; external compound sense organ; adult segment; portion of tissue; thoracic segment; synapse; tracheal system.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Insulin receptor substrate-1, PTB; Pleckstrin homology domain; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 12-24 hour embryonic stages.