Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name chico
Flybase description The gene chico is referred to in FlyBase by the symbol Dmel\chico (CG5686, FBgn0024248).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.7157 -1.8211 -4.129868 -2.5701 -9.199903 -3.5329 -2.35991 -5.87759
    Affimetrix absolute value 6.987 6.77 6.223 7.049 5.699 6.745 7.325 5.839
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: insulin-like growth factor receptor binding.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; multicellular organism reproduction; cellular component organization or biogenesis; growth; response to stress; developmental growth; gamete generation; male germ-line stem cell division; response to nutrient levels; aging.
17 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; adult; external compound sense organ; adult segment; portion of tissue; thoracic segment; synapse; tracheal system.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Insulin receptor substrate-1, PTB; Pleckstrin homology domain; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 12-24 hour embryonic stages.