Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Mekk1
Flybase description The gene Mekk1 is referred to in FlyBase by the symbol Dmel\Mekk1 (CG7717, FBgn0024329).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.73 -1.1996 -2.161656 -1.5186 -4.164511 -2.1746 -1.86463 -3.080983
    Affimetrix absolute value 6.964 7.367 7.088 7.806 6.773 7.461 7.717 6.682
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; cellular process; response to stress; response to stimulus; immune response; macromolecule modification; hyperosmotic salinity response; cellular component organization or biogenesis; cellular response to metal ion; cellular response to arsenic-containing substance.
26 alleles are reported.
The phenotype of these alleles is annotated with: wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.