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|Flybase description||The gene E2F transcription factor 2 is referred to in FlyBase by the symbol Dmel\E2f2 (CG1071, FBgn0024371).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: oocyte anterior/posterior axis specification; negative regulation of transcription from RNA polymerase II promoter; negative regulation of DNA replication; DNA endoreduplication; oocyte dorsal/ventral axis specification.
25 alleles are reported.
The phenotypes of these alleles are annotated with: chorion; eye; follicle cell; ommatidium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: E2F Family; Transcription factor E2F/dimerisation partner (TDP); Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.