Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name EfTuM
Flybase description The gene Elongation factor Tu mitochondrial is referred to in FlyBase by the symbol Dmel\EfTuM (CG6050, FBgn0024556).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.2664 1.2053 1.284269 1.2257 -0.33268 0.3846 1.76418 1.237866
    Affimetrix absolute value 8.079 7.887 8.536 8.677 8.759 8.629 9.362 8.53
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: translation elongation factor activity.
There is experimental evidence that it is involved in the biological process: Golgi organization; mitotic cell cycle; cell proliferation.
8 alleles are reported.
The phenotypes of these alleles are annotated with: digestive system; somatic muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein synthesis factor, GTP-binding; Small GTP-binding protein domain; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu/EF1A, bacterial/organelle; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation/initiation factor/Ribosomal, beta-barrel.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.