Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name NitFhit
Flybase description The gene Nitrilase and fragile histidine triad fusion protein is referred to in FlyBase by the symbol Dmel\NitFhit (CG7067, FBgn0024945).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.2009 -0.4759 -1.301733 -1.3662 -1.98107 -1.4119 -1.56826 -1.768807
    Affimetrix absolute value 8.668 7.433 7.804 7.943 7.777 8.069 7.906 7.474
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: bis(5'-adenosyl)-triphosphatase activity.
There is experimental evidence that it is involved in the biological process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Histidine triad (HIT) protein; Histidine triad motif; Histidine triad, conserved site; Histidine triad-like motif; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.