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|Flybase description||The gene supercoiling factor is referred to in FlyBase by the symbol Dmel\scf (CG9148, FBgn0025682).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: DNA topoisomerase activity.
There is experimental evidence that it is involved in the biological process: chromatin organization; dosage compensation, by hyperactivation of X chromosome; positive regulation of transcription, DNA-dependent.
8 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-18 hour embryonic stages, during early larval stages, during early pupal stages.