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|Flybase description||The gene Smad on X is referred to in FlyBase by the symbol Dmel\Smox (CG2262, FBgn0025800).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: transforming growth factor beta receptor, cytoplasmic mediator activity.
There is experimental evidence that it is involved in the biological process: axon guidance; neuron development; regulation of mitotic cell cycle; mushroom body development; imaginal disc-derived wing morphogenesis.
16 alleles are reported.
The phenotypes of these alleles are annotated with: medulla neuropil; lamina anlage glial cell; medulla neuropil glial cell; larval inner optic anlage; larval outer optic anlage; chaeta; wing; lamina.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Dwarfin; MAD homology 1, Dwarfin-type; MAD homology, MH1; SMAD domain, Dwarfin-type; SMAD domain-like; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.