Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sbf
Flybase description The gene SET domain binding factor is referred to in FlyBase by the symbol Dmel\Sbf (CG6939, FBgn0025802).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.3311 -2.6596 -5.957488 -4.078 -8.725843 -4.5753 -4.95114 -7.828026
    Affimetrix absolute value 5.996 6.235 5.649 6.379 5.68 6.369 6.264 5.38
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: diacylglycerol binding; protein tyrosine/serine/threonine phosphatase activity.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle.
2 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: DENN; GRAM; Myotubularin phosphatase domain; Myotubularin protein; Myotubularin-related; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase C-like, phorbol ester/diacylglycerol binding; dDENN; uDENN.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.