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|Flybase description||The gene Topoisomerase 3β is referred to in FlyBase by the symbol Dmel\Top3β (CG3458, FBgn0026015).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA topoisomerase activity; endodeoxyribonuclease activity.
There is experimental evidence that it is involved in the biological process: DNA catabolic process, endonucleolytic.
15 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA topoisomerase, type IA; DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, active site; DNA topoisomerase, type IA, central; DNA topoisomerase, type IA, central region, subdomain 1; DNA topoisomerase, type IA, central region, subdomain 2; DNA topoisomerase, type IA, core domain; DNA topoisomerase, type IA, domain 2; Toprim domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.