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|Flybase description||The gene Adenosine deaminase acting on RNA is referred to in FlyBase by the symbol Dmel\Adar (CG12598, FBgn0026086).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: double-stranded RNA adenosine deaminase activity.
There is experimental evidence that it is involved in the biological process: response to hypoxia; adult behavior; locomotory behavior; adenosine to inosine editing; adult locomotory behavior; response to heat; mRNA modification; regulation of membrane potential.
29 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; adult segment; adult; multicellular structure; protocerebrum; eo support cell; thoracic segment; external compound sense organ; sense organ; integumentary plate; peripheral nervous system.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Adenosine deaminase/editase; Double-stranded RNA-binding; Double-stranded RNA-binding-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.