Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mbo
Flybase description The gene members only is referred to in FlyBase by the symbol Dmel\mbo (CG6819, FBgn0026207).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.7681 -6.1893 -8.462472 -8.4282 -13.320529 -8.1244 -12.01614 -10.949028
    Affimetrix absolute value 5.291 4.994 5.098 5.325 5.062 5.555 5.004 4.811
    Affymetric present call in "x" number of chips 1 3 2 2 0 2 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: negative regulation of protein export from nucleus; antimicrobial humoral response; protein import into nucleus; neurogenesis.
10 alleles are reported.
The phenotypes of these alleles are annotated with: mesothoracic tergum; embryonic/larval dorsal anastomosis; embryonic/larval dorsal branch.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nuclear pore complex, nucleoporin 88.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.