Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Traf4
Flybase description The gene TNF-receptor-associated factor 4 is referred to in FlyBase by the symbol Dmel\Traf4 (CG3048, FBgn0026319).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.5738 -10.9096 -9.855174 -9.7411 -27.197551 -14.1128 -4.67911 -15.997875
    Affimetrix absolute value 3.495 4.177 4.995 5.121 3.998 4.808 6.359 4.303
    Affymetric present call in "x" number of chips 0 3 3 3 0 3 3 2
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: instar larval development; eye development; asymmetric protein localization involved in cell fate determination; imaginal disc fusion, thorax closure; embryo development; autophagic cell death; positive regulation of JNK cascade; positive regulation of apoptosis; salivary gland cell autophagic cell death; phagocytosis, engulfment.
15 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; eye photoreceptor cell; imaginal disc; ommatidium; ventral furrow.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: MATH; Seven In Absentia Homolog-type; TNF receptor-associated factor TRAF; TRAF-like; TRAF-type; Zinc finger, TRAF-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.